Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
نویسندگان
چکیده
منابع مشابه
Cultured dermal papilla cells induce follicle formation and hair growth by transdifferentiation of an adult epidermis.
Adult rat pelage follicle dermal papilla cells induced follicle neogenesis and external hair growth when associated with adult footpad skin epidermis. They thus demonstrated a capacity to completely change the structural arrangement and gene expression of adult epidermis--an ability previously undocumented for cultured adult cells. Isolation chambers ensured that de novo follicle formation must...
متن کاملActivation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth
The hair follicle dermal papilla (DP) contains a unique prominin-1/CD133-positive (CD133+) cell subpopulation, which has been shown to possess hair follicle-inducing capability. By assaying for endogenous CD133 expression and performing lineage tracing using CD133-CreERT2; ZsGreen1 reporter mice, we find that CD133 is expressed in a subpopulation of DP cells during the growth phase of the murin...
متن کاملAcute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells: Implications for Hair Growth
BACKGROUND Stress is a known cause of hair loss in many species. OBJECTIVE In this study, we investigated the role of acute stress on hair growth using a rat model. METHODS Rats were immobilized for 24 hours and blood samples, and skin biopsies were taken. The effect of stress-serum on the in vitro proliferation of rat and human dermal papilla cells (hDPCs), as well as serum cortisol and co...
متن کاملMicroenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth.
De novo organ regeneration has been observed in several lower organisms, as well as rodents; however, demonstrating these regenerative properties in human cells and tissues has been challenging. In the hair follicle, rodent hair follicle-derived dermal cells can interact with local epithelia and induce de novo hair follicles in a variety of hairless recipient skin sites. However, multiple attem...
متن کاملHair follicle dermal papilla cells at a glance.
Ryan R. Driskell1, Carlos Clavel2, Michael Rendl2,* and Fiona M. Watt1,3,* 1Laboratory for Epidermal Stem Cell Biology, Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge CB2 1QR, UK 2Black Family Stem Cell Institute and Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029, USA 3CRUK Cambridge Research Institute, ...
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ژورنال
عنوان ژورنال: Annals of Dermatology
سال: 2019
ISSN: 1013-9087,2005-3894
DOI: 10.5021/ad.2019.31.2.164